Kisspeptin-10 dosing calculator
1 mg = 1000 mcg.
0.020 mL · 5,000 mcg/mL
- Doses per vial
- 100
- Per unit
- 50 mcg
- One vial lasts
- 100 days at 1/day
Your draw
www.undergroundbiohacking.com · For tracking and calculation purposes only. Not medical advice.
For tracking and calculation purposes only. Not medical advice. Based on a standard U-100 insulin syringe.
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How the units are worked out
Your vial holds a fixed amount of peptide. The water you add sets the concentration (how much peptide sits in each millilitre). The concentration then decides how much liquid carries your dose.
Three steps, in order:
- Concentration (mcg/mL) = peptide in the vial (mcg) divided by water added (mL).
- Volume (mL) = your dose (mcg) divided by the concentration (mcg/mL).
- Units to draw = volume (mL) multiplied by 100.
That last step is the syringe, not the peptide. A U-100 insulin syringe is marked so 100 units hold 1 mL, so 0.1 mL reads as 10 units.
A worked example
These are the numbers in the calculator above, worked through: 10 mg + 2 mL = 5,000 mcg/mL. 100 mcg = 0.02 mL = 2 units on a 0.3 mL syringe.
Change any number in the tool and this line changes with it. The link in your address bar carries the numbers, so you can save it or send it to yourself.
Water and units at a glance
The same dose of Kisspeptin-10 at different mixes. Every row opens the calculator on that mix.
| Vial | Water | Concentration | Units to draw |
|---|---|---|---|
| 10 mg | 1 mL | 10,000 mcg/mL | 1 units |
| 10 mg | 2 mL | 5,000 mcg/mL | 2 units |
| 10 mg | 3 mL | 3,333 mcg/mL | 3 units |
| 10 mg | 5 mL | 2,000 mcg/mL | 5 units |
Pre-filled numbers are the most-used setups reported by users of public calculators (WPA dosing data, Aug 2026). Not a recommendation.
Mixing and storage
Run the water down the inside wall of the vial and let the powder dissolve on its own. Never shake it. Label the vial with the compound, the total mass, the water you added, the concentration and the date. A sealed freeze-dried vial keeps 12 to 24 months in the fridge at 2 to 8°C. Once mixed with preserved water, such as bacteriostatic water, that drops to roughly 28 days refrigerated. Keep it at the back of the fridge, away from light and away from the door's temperature swings.
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Questions
Does kisspeptin-10 raise testosterone?
Does kisspeptin-10 improve libido?
Is kisspeptin-10 the same thing as kisspeptin-54?
Does it work the same way in women and in men?
Is kisspeptin-10 legal?
What should I ask a doctor about it?
References
- 01Ohtaki T, et al. (2001). Metastasis suppressor gene KiSS-1 encodes peptide ligand of a G-protein-coupled receptor. Nature. PMID: 11385580. DOI: 10.1038/35079135.
- 02Hori A, et al. (2001). Metastin suppresses the motility and growth of CHO cells transfected with its receptor. Biochemical and biophysical research communications. PMID: 11527393. DOI: 10.1006/bbrc.2001.5470.
- 03Dhillo WS, et al. (2005). Kisspeptin-54 stimulates the hypothalamic-pituitary gonadal axis in human males. The Journal of clinical endocrinology and metabolism. PMID: 16174713. DOI: 10.1210/jc.2005-1468.
- 04George JT, et al. (2011). Kisspeptin-10 is a potent stimulator of LH and increases pulse frequency in men. The Journal of clinical endocrinology and metabolism. PMID: 21632807. DOI: 10.1210/jc.2011-0089.
- 05Jayasena CN, et al. (2011). The effects of kisspeptin-10 on reproductive hormone release show sexual dimorphism in humans. The Journal of clinical endocrinology and metabolism. PMID: 21976724. DOI: 10.1210/jc.2011-1408.
- 06MacLean DB, et al. (2014). Sustained exposure to the investigational Kisspeptin analog, TAK-448, down-regulates testosterone into the castration range in healthy males and in patients with prostate cancer: results from two phase 1 studies. The Journal of clinical endocrinology and metabolism. PMID: 24762108. DOI: 10.1210/jc.2013-4236.
- 07Comninos AN, et al. (2017). Kisspeptin modulates sexual and emotional brain processing in humans. The Journal of clinical investigation. PMID: 28112678. DOI: 10.1172/JCI89519.
- 08Millar RP, et al. (2017). Hypothalamic-Pituitary-Ovarian Axis Reactivation by Kisspeptin-10 in Hyperprolactinemic Women With Chronic Amenorrhea. Journal of the Endocrine Society. PMID: 29264460. DOI: 10.1210/js.2017-00328.
- 09Thurston L, et al. (2022). Effects of Kisspeptin Administration in Women With Hypoactive Sexual Desire Disorder: A Randomized Clinical Trial. JAMA network open. PMID: 36287566. DOI: 10.1001/jamanetworkopen.2022.36131.
- 10Mills EG, et al. (2023). Effects of Kisspeptin on Sexual Brain Processing and Penile Tumescence in Men With Hypoactive Sexual Desire Disorder: A Randomized Clinical Trial. JAMA network open. PMID: 36735255. DOI: 10.1001/jamanetworkopen.2022.54313.
By Chris Hallewell, Founder, Underground Biohacking
Last reviewed
The numbers here describe your own vial. They are not medical advice and not a dose suggestion. Confirm your protocol with a qualified clinician.
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