Ipamorelin dosing calculator

CompoundIpamorelin

Vial

Water

Your dose

1 mg = 1000 mcg.

Your syringe

Draw this much

0.0units

0.040 mL · 5,000 mcg/mL

0 units0.3 mL barrel, U-100 scale30 units

Doses per vial: 50
Per unit: 50 mcg
One vial lasts: 50 days at 1/day

Reference only · Not medical advice

Your draw

Vial10 mg

Water2 mL

Concentration5,000 mcg/mL

Dose200 mcg

Draw4 units

Syringe0.3 mL, U-100

www.undergroundbiohacking.com · For tracking and calculation purposes only. Not medical advice.

For tracking and calculation purposes only. Not medical advice. Based on a standard U-100 insulin syringe.

How the units are worked out

Your vial holds a fixed amount of peptide. The water you add sets the concentration (how much peptide sits in each millilitre). The concentration then decides how much liquid carries your dose.

Three steps, in order:

Concentration (mcg/mL) = peptide in the vial (mcg) divided by water added (mL).
Volume (mL) = your dose (mcg) divided by the concentration (mcg/mL).
Units to draw = volume (mL) multiplied by 100.

That last step is the syringe, not the peptide. A U-100 insulin syringe is marked so 100 units hold 1 mL, so 0.1 mL reads as 10 units.

A worked example

These are the numbers in the calculator above, worked through: 10 mg + 2 mL = 5,000 mcg/mL. 200 mcg = 0.04 mL = 4 units on a 0.3 mL syringe.

Change any number in the tool and this line changes with it. The link in your address bar carries the numbers, so you can save it or send it to yourself.

Water and units at a glance

The same dose of Ipamorelin at different mixes. Every row opens the calculator on that mix.

Vial	Water	Concentration	Units to draw
10 mg	1 mL	10,000 mcg/mL	2 units
10 mg	2 mL	5,000 mcg/mL	4 units
10 mg	3 mL	3,333 mcg/mL	6 units
10 mg	5 mL	2,000 mcg/mL	10 units

Pre-filled numbers are the most-used setups reported by users of public calculators (WPA dosing data, Aug 2026). Not a recommendation.

Mixing and storage

Run the water down the inside wall of the vial and let the powder dissolve on its own. Never shake it. Label the vial with the compound, the total mass, the water you added, the concentration and the date. A sealed freeze-dried vial keeps 12 to 24 months in the fridge at 2 to 8°C. Once mixed with preserved water, such as bacteriostatic water, that drops to roughly 28 days refrigerated. Keep it at the back of the fridge, away from light and away from the door's temperature swings.

Other compounds

Questions

Does ipamorelin actually raise growth hormone in people?

Yes. That part is settled. A study in healthy male volunteers measured growth hormone in the blood after ipamorelin was infused. It produced one burst that peaked inside the first hour and then dropped back towards nothing. That is the strongest human finding on this peptide. Note what it does not show. Raising growth hormone for an hour is not the same as changing your muscle, your fat or your health.

Did ipamorelin ever fail a clinical trial?

Yes, and this is the part most write ups leave out. It was tested in a randomised, placebo controlled phase 2 trial in patients recovering from bowel surgery. The target was postoperative ileus, where the gut stops moving after an operation. Ipamorelin did not beat placebo on the main measure or the secondary ones. The programme did not go on to succeed. That is the only efficacy trial in people that has been published.

Is ipamorelin really selective, with no cortisol or prolactin spike?

The claim traces back to one 1998 paper, and it was measured in pigs, not people. In that work ipamorelin raised growth hormone but left ACTH and cortisol alone, even at doses far above the level needed for growth hormone. None of the peptides tested changed prolactin, TSH, LH or FSH. So the selectivity claim is real published science, but it is animal science. No human study has repeated it.

Will ipamorelin build muscle or help me lose fat?

No study in people has tested that. The muscle and bone findings come from rats given steroids that waste tissue, where ipamorelin restored some muscle force and bone building. Rats are not a body composition trial. Working the other way, mice given secretagogues of this type gained body fat and ate more, by a route that did not involve growth hormone. So the animal picture on fat is not the one the marketing suggests.

Is ipamorelin safe?

Nobody can answer that properly. In the surgery trial, side effects were common in both groups. They were no worse on ipamorelin than on placebo. But that was one small study over a few days. There is no long term human safety data. FDA notes an immune reaction risk with compounded versions and reports of serious adverse events, including death, in published intravenous use. Animal work also flags more insulin release and more appetite.

What should I ask a doctor about ipamorelin?

Ask what problem you are actually trying to fix, and whether a tested treatment exists for it. Ask for baseline blood work, including blood sugar and IGF-1, before anything starts. Ask what would count as a sign to stop. Tell them plainly if you already use it, because it can shift hormone and glucose results and change how your tests read. Ask them to explain the regulatory position, since ipamorelin is not an approved medicine.