Underground Biohacking
Growth hormone

CJC-1295 and Sleep Optimization: What Has Been Studied

What the research covers

No published study was found that measured sleep in people or animals given CJC-1295. The human studies measured growth hormone and IGF-I in healthy adults. CJC-1295 is a lab-made form of GHRH, a hormone that drives the release of growth hormone (GH). After a shot, it binds to albumin, a blood protein, so it lasts much longer than natural GHRH.

One study took blood every 20 minutes over 12 hours overnight. Healthy men aged 20 to 40 were tested before and one week after one shot of 60 or 90 micrograms per kilogram. GH still came in pulses, at the same rate and size as before. The level between pulses rose 7.5 times. The study measured hormones in blood, not sleep.

Two trials tested it against placebo in healthy adults aged 21 to 61. The shots went under the skin. The trials ran for 28 and 49 days. The estimated half-life was 5.8 to 8.1 days. No serious adverse reactions were reported.

A PubMed search on 27 September 2026 found no study of CJC-1295 and sleep. The two hits were a review and a study of online posts.

Sources

  1. Ionescu M, Frohman LA Pulsatile secretion of growth hormone (GH) persists during continuous stimulation by CJC-1295, a long-acting GH-releasing hormone analog. J Clin Endocrinol Metab (2006). PMID 17018654 doi:10.1210/jc.2006-1702
  2. Teichman SL, Neale A, Lawrence B, et al. Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults. J Clin Endocrinol Metab (2006). PMID 16352683 doi:10.1210/jc.2005-1536

Frequently Asked Questions

Has CJC-1295 been tested for sleep?
None was found. A PubMed search on 27 September 2026 found no study that measured sleep in people or animals given CJC-1295.
Did any CJC-1295 study collect data overnight?
Yes, one study took blood every 20 minutes over 12 hours overnight. A week after one shot, GH pulses kept the same rate and size. The level between pulses rose 7.5 times. The study did not measure sleep.
What dose was used in the overnight study?
Healthy men aged 20 to 40 got one shot of 60 or 90 micrograms per kilogram. The two doses gave no significant difference in response.
How long does CJC-1295 last in the body?
In healthy adults, its estimated half-life was 5.8 to 8.1 days. One shot raised GH levels for 6 days or more.

More CJC-1295 research

Deep dives on CJC-1295

This content is for educational purposes only. These compounds are intended for research use. Nothing here is medical advice.

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