Sleep

DSIP

Mechanism

Delta-sleep-inducing peptide. A nonapeptide that crosses the blood-brain barrier. Modulates HPA-axis activity and increases delta-wave (slow-wave) sleep architecture. Also studied for stress resilience and chronic pain.

Typical dose

100-300mcg per dose, 30 minutes before sleep

Cycle length

4-8 weeks; pulsed use also common

Form

Injectable (subcutaneous), intranasal

Deep dives on DSIP

What the FDA Reclassification Actually Means for Peptide UsersFDA peptide reclassification 2026: what Category 2 to Category 1 actually means for users, what's changed, what hasn't, and what to expect from the July PCAC meeting.
Which Peptides Are Legal Again in 2026? The Full FDA ListComplete guide to the 14 peptides returning to legal compounding status in 2026 after RFK Jr.'s FDA reclassification announcement. Every compound explained.

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