Selank and Sleep Optimization: What Has Been Studied
What the research covers
A PubMed search found no study of Selank for sleep or insomnia. Its trials in patients were small Russian studies in anxiety, and none tested it as a sleep treatment.
One trial gave 62 patients with anxiety or nervous exhaustion either selank or medazepam. Both drugs eased anxiety to a similar degree. A second study gave 60 patients with anxiety selank or phenazepam.
One trial touched on sleep only as a side effect. A third trial gave 70 patients with anxiety phenazepam, with or without selank. Adding selank cut the side effects of phenazepam. Those side effects included drowsiness and longer sleep. The trial did not measure insomnia or sleep quality as a main result.
In a rodent (rat) study, selank changed the activity of genes involved in GABA signalling in the brain. The authors suggested selank may act on the GABA system. No human study found for this page linked this to sleep.
Sources
- Medvedev VE, Tereshchenko ON, Kost NV, et al. Optimization of the treatment of anxiety disorders with selank Zh Nevrol Psikhiatr Im S S Korsakova (2015). PMID 26356395 doi:10.17116/jnevro20151156133-40 Russian trial, 70 patients with anxiety disorders; selank added to phenazepam reduced its side effects, including sedation and longer sleep.
- Zozulia AA, Neznamov GG, Siuniakov TS, et al. Efficacy and possible mechanisms of action of a new peptide anxiolytic selank in the therapy of generalized anxiety disorders and neurasthenia Zh Nevrol Psikhiatr Im S S Korsakova (2008). PMID 18454096 Russian trial, 62 patients with generalised anxiety disorder or neurasthenia; selank compared with medazepam.
- Medvedev VE, Tereshchenko ON, Israelian AIu, et al. A comparison of the anxiolytic effect and tolerability of selank and phenazepam in the treatment of anxiety disorders Zh Nevrol Psikhiatr Im S S Korsakova (2014). PMID 25176261 Russian study, 60 patients with anxiety and somatoform disorders; selank compared with phenazepam.
- Volkova A, Shadrina M, Kolomin T, et al. Selank Administration Affects the Expression of Some Genes Involved in GABAergic Neurotransmission Front Pharmacol (2016). PMID 26924987 doi:10.3389/fphar.2016.00031 Rodent (rat) study: selank changed the activity of genes involved in GABA signalling.
Where to buy Selank
The hard part with Selank isn't the protocol. It's finding a supplier that can prove what's in the vial. We assessed dozens against per-batch, third-party testing. A handful passed.
See the sources that passed →Frequently Asked Questions
Has Selank been tested for sleep?
What did Selank trials in anxiety find?
Did any Selank trial report effects related to sleep?
How is Selank thought to act on the brain?
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This content is for educational purposes only. These compounds are intended for research use. Nothing here is medical advice.
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